{"id":10220,"date":"2021-06-09T04:46:53","date_gmt":"2021-06-09T02:46:53","guid":{"rendered":"https:\/\/www.congen.de\/praezisionsmedizin\/"},"modified":"2024-07-24T09:41:49","modified_gmt":"2024-07-24T07:41:49","slug":"precision-medicine","status":"publish","type":"page","link":"https:\/\/www.congen.de\/en\/precision-medicine\/","title":{"rendered":"Precision Medicine"},"content":{"rendered":"

[et_pb_section fb_built=”1″ fullwidth=”on” admin_label=”Header (Bild + Headlines)” _builder_version=”4.16″ background_image=”https:\/\/www.congen.de\/wp-content\/uploads\/Congen-Personalisierte-Medizin\u00a9Dreamstime-MichaelBrown-2.jpg” global_colors_info=”{}”][et_pb_fullwidth_header title=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF90aXRsZSIsInNldHRpbmdzIjp7ImJlZm9yZSI6IiIsImFmdGVyIjoiIn19@” subhead=”Diagnostische Tests f\u00fcr zielgerichtete Therapien ” button_one_text=”Testkits” button_one_url=”#Nachweise” button_two_text=”Qualit\u00e4t” button_two_url=”https:\/\/www.congen.de\/en\/quality-standards\/” content_max_width=”900px” admin_label=”Header Elemente” _builder_version=”4.16″ _dynamic_attributes=”title,background_image” title_font=”|700||on|||||” title_font_size=”48px” title_line_height=”1.1em” content_text_align=”left” content_font_size=”24px” content_line_height=”1.5em” subhead_font=”||||||||” subhead_text_align=”left” subhead_font_size=”32px” subhead_line_height=”1.2em” background_color=”rgba(126,190,197,0)” use_background_color_gradient=”on” background_color_gradient_direction=”90deg” background_color_gradient_stops=”#056b9a 25%|rgba(5,107,154,0.3) 75%” background_color_gradient_overlays_image=”on” background_color_gradient_start=”#056b9a” background_color_gradient_start_position=”25%” background_color_gradient_end=”rgba(5,107,154,0.3)” background_color_gradient_end_position=”75%” background_image=”@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9mZWF0dXJlZF9pbWFnZSIsInNldHRpbmdzIjp7fX0=@” custom_button_one=”on” button_one_text_color=”#056b9a” button_one_bg_color=”#ffffff” button_one_border_width=”2px” button_one_border_color=”#ffffff” button_one_letter_spacing=”1″ button_one_font=”|500||on|||||” button_one_use_icon=”off” custom_button_two=”on” button_two_text_color=”#056b9a” button_two_bg_color=”#ffffff” button_two_border_color=”#ffffff” button_two_letter_spacing=”1″ button_two_font=”|500||on|||||” button_two_use_icon=”off” custom_padding=”8vw||8vw||true|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”6vw||6vw||true|false” custom_padding_last_edited=”on|phone” title_font_size_tablet=”36px” title_font_size_phone=”24px” title_font_size_last_edited=”on|phone” content_font_size_tablet=”18px” content_font_size_phone=”14px” content_font_size_last_edited=”on|phone” subhead_font_size_tablet=”24px” subhead_font_size_phone=”18px” subhead_font_size_last_edited=”on|desktop” button_one_text_size_tablet=”” button_one_text_size_phone=”14px” button_one_text_size_last_edited=”on|tablet” button_two_text_size_tablet=”” button_two_text_size_phone=”14px” button_two_text_size_last_edited=”on|tablet” custom_css_title=”margin-bottom: 0.5em;||padding: 0;” custom_css_subtitle=”margin-bottom: 1em;||padding: 0;” button_one_text_color_hover=”#ffffff” button_two_text_color_hover=”#ffffff” button_one_border_color_hover=”rgba(255,255,255,0)” button_two_border_color_hover=”rgba(255,255,255,0)” button_one_bg_color_hover=”rgba(255,255,255,0.33)” button_two_bg_color_hover=”rgba(255,255,255,0.33)” global_colors_info=”{}” button_one_text_size__hover_enabled=”off” button_two_text_size__hover_enabled=”off” button_one_text_color__hover_enabled=”on” button_one_text_color__hover=”#ffffff” button_two_text_color__hover_enabled=”on” button_two_text_color__hover=”#ffffff” button_one_border_width__hover_enabled=”off” button_two_border_width__hover_enabled=”off” button_one_border_color__hover_enabled=”on” button_one_border_color__hover=”rgba(255,255,255,0)” button_two_border_color__hover_enabled=”on” button_two_border_color__hover=”rgba(255,255,255,0)” button_one_border_radius__hover_enabled=”off” button_two_border_radius__hover_enabled=”off” button_one_letter_spacing__hover_enabled=”off” button_two_letter_spacing__hover_enabled=”off” button_one_bg_color__hover_enabled=”on” button_one_bg_color__hover=”rgba(255,255,255,0.33)” button_two_bg_color__hover_enabled=”on” button_two_bg_color__hover=”rgba(255,255,255,0.33)”]<\/p>\n

\/\/ individuell & effektiv<\/p>\n

\/\/ hochspezifisch & eindeutig<\/p>\n

[\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_row column_structure=”2_3,1_3″ use_custom_gutter=”on” module_id=”CN-Products” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_column type=”2_3″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”][et_pb_text admin_label=”Introtext” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

Pr\u00e4zisionsmedizin<\/h2>\n

Anspruch der modernen Gesundheitsforschung ist das h\u00f6chste Ma\u00df therapeutischer Wirksamkeit bei gleichzeitig minimalsten Nebenwirkungen. Aufgrund seiner individuellen genetischen Konstitution spricht jeder Mensch unterschiedlich auf eine medikament\u00f6se Therapie an. Die gro\u00dfen Fortschritte in der Grundlagenforschung in den letzten Jahren, inklusive Molekularbiologie, Genomik und Bioinformatik haben u.a. zum besseren Verst\u00e4ndnis molekularer Prozesse bei der Entstehung von Krankheiten gef\u00fchrt. In Kombination mit weiteren Informationen \u00fcber den Gesundheitszustand und den Lebensstil lassen sich neue Therapieformen ableiten. Die moderne Diagnostik versucht bei bestimmten Medikamenten oder Behandlungen anhand dieser Informationen genauer vorherzusagen, bei wem sie wirken und bei wem nicht. Das Ziel jeden Menschen entsprechend seiner Bed\u00fcrfnisse individuell behandeln zu k\u00f6nnen, ist damit n\u00e4her ger\u00fcckt.<\/p>\n

Derzeit werden stratifizierte Therapieformen entwickelt, was bedeutet, dass die Patienten in risikoangepasste Behandlungsgruppen geordnet werden, die auf molekularer Ebene unterschiedlich auf Medikamente ansprechen.<\/p>\n

Vor der Entscheidung, ob eine bestimmte Therapieform sinnvoll ist, findet eine genaue Diagnostik statt. Hier werden oft Daten aus Labortests herangezogen, die bestimmte Blutwerte messen oder Erbgutver\u00e4nderungen analysieren. Die Grundlage daf\u00fcr ist die Kenntnis \u00fcber bestimmte biologische Merkmale, kurz Biomarker. Viele dieser Biomarker sind erst seit kurzem bekannt. Mit real-time PCR lassen sich viele Biomarker einfach und ohne die Notwendigkeit einer Gewebeprobe (Biopsie) nachweisen. Der Begriff \u201ePersonalisierte Medizin\u201c bzw. Pr\u00e4zisionsmedizin wird daher haupts\u00e4chlich f\u00fcr die Anwendung bestimmter diagnostischer Tests verwendet, mit denen dann eine ausgew\u00e4hlte Therapie folgt.<\/p>\n

Vor dem Hintergrund aktueller Studien entwickelt CONGEN,<\/strong><\/span> sowohl in eigener Forschung als auch im Auftrag, hoch-spezifische diagnostische Schnelltestsysteme und unterst\u00fctzt auf diese Weise effizient das Therapiekonzept der personalisierten Medizin.<\/p>\n

Ein Beispiel ist der, in Zusammenarbeit mit HMNC Brain Health und dem Max-Planck-Institut f\u00fcr Psychatrie M\u00fcnchen und von CONGEN,<\/strong><\/span> entwickelte Multiplex real-time PCR zum Nachweis der ABCB1-Genvarianten (sogenannte SNPs, engl. single nucleotide polymorphisms<\/i>). Dieser Test unterst\u00fctzt die Behandlung von Depressionen mit spezifischen Antidepressiva. Anhand der Genvarianten k\u00f6nnen Patienten identifiziert werden, bei denen viele der g\u00e4ngigen Antidepressiva die Blut-Hirn-Schranke weniger leicht passieren k\u00f6nnen und die daher schlechter auf die Therapie ansprechen. <\/p>\n

Ein weiteres Beispiel ist der Nachweis von HLA-B27 Subtypen mit real-time PCR. Das Humane Leukozyten-Antigen-B27 (HLA-B27) ist ein Zelloberfl\u00e4chenantigen dessen Funktion es ist, den T-Zellen bestimmte mikrobielle Antigene zu pr\u00e4sentieren. Der Test kann unterst\u00fctzend zur Diagnose von Patienten mit Verdacht auf eine chronische rheumatische Krankheit (Spondylitis ankylosans- auch Morbus Bechterew genannt) und andere Autoimmunkrankheiten eingesetzt werden.<\/p>\n

[\/et_pb_text][et_pb_text admin_label=”Subheadline Produkte” module_id=”Nachweise” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n

VERF\u00dcGBARE TESTKITS<\/h3>\n

[\/et_pb_text][et_pb_toggle title=”Genotypisierung” admin_label=”Umschalter Produktuntergruppe” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n\n\n\n\n\t\n\n\t
Produktname<\/th>Markierung<\/th>Produktnummer<\/th>\n<\/tr>\n<\/thead>\n
RIDA\u00ae<\/sup>GENE HLA-B27<\/span><\/td><\/td>PY0205<\/span><\/i><\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

[\/et_pb_toggle][et_pb_toggle title=”Therapeutische Diagnostik” admin_label=”Umschalter Produktuntergruppe” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}”]<\/p>\n\n\n\n\n\t\n\n\t
Produktname<\/th>Markierung<\/th>Produktnummer<\/th>\n<\/tr>\n<\/thead>\n
RIDA\u00ae<\/sup>PRECISION ABCB1<\/span><\/td><\/td>Y5500<\/span><\/i><\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

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\"R-Biopharm\"<\/p>\n

Sie interessieren sich f\u00fcr weiterf\u00fchrende Informationen zu einem oder mehreren der entwickelten Nachweiskits? Sie m\u00f6chten ausgew\u00e4hlte Kits bestellen?<\/p>\n

Wenden Sie sich vertrauensvoll an unseren\u00a0 Vertriebspartner R-Biopharm.<\/p>\n

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\/\/ individuell & effektiv \/\/ hochspezifisch & eindeutig Pr\u00e4zisionsmedizin Anspruch der modernen Gesundheitsforschung ist das h\u00f6chste Ma\u00df therapeutischer Wirksamkeit bei gleichzeitig minimalsten Nebenwirkungen. Aufgrund seiner individuellen genetischen Konstitution spricht jeder Mensch unterschiedlich auf eine medikament\u00f6se Therapie an. Die gro\u00dfen Fortschritte in der Grundlagenforschung in den letzten Jahren, inklusive Molekularbiologie, Genomik und Bioinformatik haben u.a. zum […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-10220","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"\nPrecision Medicine - 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